Sindrome de trisomia1/31/2023 People with this genetic change are said to have partial trisomy 18. Affected individuals have two copies of chromosome 18, plus the extra material from chromosome 18 attached to another chromosome. Very rarely, part of the long (q) arm of chromosome 18 becomes attached (translocated) to another chromosome during the formation of reproductive cells (eggs and sperm) or very early in embryonic development. The development of individuals with this form of trisomy 18 may range from normal to severely affected. The severity of mosaic trisomy 18 depends on the type and number of cells that have the extra chromosome. In these people, the condition is called mosaic trisomy 18. The extra genetic material disrupts the normal course of development, causing the characteristic features of trisomy 18.Īpproximately 5 percent of people with trisomy 18 have an extra copy of chromosome 18 in only some of the body's cells. Most cases of trisomy 18 result from having three copies of chromosome 18 in each cell in the body instead of the usual two copies.
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |